![]() ![]() Conditions that create a ‘dead space effect’ are (a) high V/Q units in a heterogenous lung, and (b) shunt. The causes of true dead space are (a) anatomical dead space and (b) alveolar dead space. V d V t = P A C O 2 − P e C O 2 P A C O 2 Ī common step is to then presume that the partial pressure of carbon dioxide in the end-tidal exhaled air is in equilibrium with that gas' tension in the blood that leaves the alveolar capillaries of the lung. Dead space represents the volume of ventilated air that does not participate in gas exchange. The original formulation by Bohr, required measurement of the alveolar partial pressure P A. The Bohr equation is used to quantify the ratio of physiological dead space to the total tidal volume, and gives an indication of the extent of wasted ventilation. It differs from anatomical dead space as measured by Fowler's method as it includes alveolar dead space. ![]() ![]() This is given as a ratio of dead space to tidal volume. The Bohr equation, named after Danish physician Christian Bohr (1855–1911), describes the amount of physiological dead space in a person's lungs. Not to be confused with the Bohr model or the Bohr effect. ![]()
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